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They may include: Mild nausea, vomiting, or diarrhea Constipation Abdominal pain or discomfort Headache These effects are usually short-lived and can often be minimized by ensuring you are well-hydrated, by adjusting your diet (e.g., avoiding fatty foods, eating smaller meals), and by gradually increasing your dose as advised by your provider

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The same dose of semaglutide that was driving robust appetite suppression may produce less dramatic caloric restriction as your caloric needs decrease